実験的ビタミンE欠乏症における生殖腺および内分泌腺の病理組織学的研究

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概要

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• Histopathological studies were made on the changes in the reproductive and endocrine organs of rats, fed on a vitamin E deficient diet. Marked degeneration and atrophy were observed in the testis. These changes were considered to be produced by the inhibition of spermatogenesis following the necrosis of spermatogonia. Electronmicroscopic studies revealed that the degeneration and necrosis of spermatogonia were caused by the degeneration and destruction of the mitochondria and endoplasmic reticulum of the testis. A remarkable proliferation of interstitial cells occurred with the degeneration and atrophy of the seinal tubes. From the electronmicroscopic pattern, it was concluded the endoplasmic reticulum concerns the granule formation in the interstitial cells. Changes of the hypophysis and adrenal systems were also investigated and the significance of the systems in vitamin E deficiency was discussed.

• 日本ビタミン学会の論文

著者

• 李 師智

  京都府立医大病理学

関連論文

• 32.シロネズミの実験的ビタミンE欠乏症の内分泌腺の変化について(第12回大会研究発表要旨)
• オロット酸の毒性に関する実験病理学的研究
• 実験的ビタミンE欠乏症における生殖腺および内分泌腺の病理組織学的研究

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