ビタミンDの雌性性機能におよぼす影響に関する実験的研究 : (II)ビタミンD欠乏および過剰シロネズミの卵巣と子宮の組織学的所見

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The author has studied, histologically, the effect of vitamin D on the ovary and the uterus of albino rat, and reached to the following conclusions. Deficiency of vitamin D affects the follicular tissues of ovaries and especially the regressive degeneration of the growing follicles, which prohibits the ovulation, is very remarkable. Along with these changes in the ovaries, the uterus becomes atrophic. But these changes are recovered by an administration of vitamin D almost to normal condition. On the other hand, the animals, which has been given small amount of vitamin D, reveal the acceleration of the follicular development and the enlargement of uterus. These facts show that vitamin D has enhanced the functions of the sexual organs. If the animals are given a large amount of vitamin D over a long period of time, it will enhance the sexual function temporarily, but then the ovaries and the uteri will become atrophic and will finally lose their function completely.
日本ビタミン学会の論文