高温環境におけるビタミンC代謝に関する実験的研究 : (I)急激な高温曝露における臓器内ビタミンC濃度について

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The effects of high temperature environment and ACTH on the ascorbic acid content in adrenal gland and other tissues of guinea pig, rabbit and albino rat were investigated. The ascorbic acid contents of liver, kidney and spleen, especially of adrenal gland decreased in case that the animals were suddenly exposed to a high temperature environment for one hour, but it was gradually restored to a normal level in subsequent 24 hours, while the decrease of the contents in the liver, kidney and spleen were only a few percent. By daily exposure to a hot environment, the rate of decrease of ascorbic acid content in the adrenal gland was reduced to lower degree, possibly because of the acclimatization or adaptation of the animals to a hot environment. The similar patterns were observed also in the ACTH administration.
日本ビタミン学会の論文