TOXOPYRIMIDINE群物質の研究 : (VI)脳TRANSAMINASEとGLUTAMIC DECARBOXYLASEにおよぼす影響

スポンサーリンク

概要

• 論文の詳細を見る

• The effect of 2-methyl-4-amino-5-hydroxymethylpyrimidine (OMP) and hydroxylamine on the enzymic system related to glutamic acid metabolism in the brain and involving vitamin B_6,that is, glutamic decarboxylase and glutamic-aspartic transaminase was studied. It was found that when a running fit is induced by OMP, the OMP is phosphorylated in the body and inhibits glutamic-aspartic transaminase but this enzyme system is not affected by hydroxylamine. Glutamic decarboxylase, on the other hand, is inhibited by both OMP and hydroxylamine and this inhibition takes place prior to the onset of the running fit. It is suggested that the inhibition of glutamic decarboxylase plays an important role in the inducement of the running fit.

• 日本ビタミン学会の論文

著者

• 難波 澄雄

  大阪大学医学部小児科学教室

関連論文

• 実験的ウサギ高血圧症に対するN-CARBOBENZOXY-L-GLUTAMYLCHOLINEの影響について
• TOXOPYRIMIDINE群物質の研究 : (VI)脳TRANSAMINASEとGLUTAMIC DECARBOXYLASEにおよぼす影響
• 急性灰白髄炎のグルタミルコリンならびにビタミンB_1併用髄腔内注入療法による皮膚温度の変動について
• 132.グルタミルコリン, コリンおよびグルタミン酸の腸内細菌発育に及ぼす影響(第5回日本ビタミン学会研究発表要旨)

スポンサーリンク