抗原侵襲による早期血清脂質の動態にかんする実験的研究 : (I)血清脂質の変動について

概要

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In the present paper, it was made to clear of the behaviors of total lipid (TL) and triglyceride (TG) in serum and their composed fatty acids provoked in early stages after primary sensitization of typhoid-paratyphoid vaccine (TPV), in rabbits, and the results obtained were as follows : (1) During several hours after the primary sensitization of TPV, both TL and TG in serum and their composed fatty acids in quantity decreased remarkably in the circulation, i.e. it will be coincided with a negative phase in vital response introduced by stress of antigen invasion, universally. And also, it may be considered that the remarkable mobilization of serum lipid in the circulation 24 hours later after the TPV invasion was provoked in compensation for the negative phase. (2) The secondary response increased abruptly TL and TG without the provocation of negative phase in early stage. (3) The main composed fatty acids, i.e. palmitic acid (P), oleic acid (O) and linoleic acid (L), etc. increased remarkably with comparision to their values in normal rabbits the ratio of P/L value increased and L/O value decreased in the percentage of fatty acids in serum, respectively.
日本ビタミン学会の論文
1968-11-25