Hydroxocobalamin注射後の血中濃度にかんする基礎研究

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概要

• 論文の詳細を見る

• Hydroxocobalamin (OH-B_<12>) and cyanocobalamin (CN-B_<12>) both labeled with ^<57>Co were compared with respect to binding by serum proteins and retention in blood following intravenous administration in rats. There was no difference in blood retention following injection of physiological doses, but disappearance of OH-B_<12> from blood was retarded compared with CN-B_<12> when given in supraphysiological doses. More OH-B_<12> was bound to serum as determined by dialysis method when its amount to be mixed with serum was increased, whereas no such increase ion binding occurred in CN-B_<12> under the same condition. There was practically no difference between human and rat sera in behavior toward these analogues.

• 日本ビタミン学会の論文
• 1966-05-25

著者

• 堤 千尋

  久留米大学医学部第二内科

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• Hydroxocobalamin注射後の血中濃度にかんする基礎研究
• タイトル無し

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