Transfer of Oxygen Supplied by Aeration in Submerged Fermentation

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概要

• 論文の詳細を見る

• Methods for the design of fermentation equipment and for the evaluation of its performance will be greatly improved by increased knowledge of the factors affecting oxygen transfer in those systems requiring some degree of aeration. Submerged fermentation methods are now almost universal in the development of new antibiotics and in practically all other fermentations of industrial significance. The provision of an oxygen supply adequate to meet the metabolic requirements of the organism employed is absolutely essential to the successful use of the techniques. Therefore it is necessary to know resistances to the transfer of oxygen supplied by aeration. The oxygen transfer in submerged fermentation is considered as a series of rate processes; the purely physical process of oxygen absorption and the metabolic process. It was verified by Calderbank's and our previous work that the gas-film resistance to gas absorption in bubbling agitated gas-liquid contactors is negligible in comparison with the liquid-film resistance.In the present work, the transfer of oxygen in bubbling aeration with mechanical agitation was studied with the propagation of bakers' yeast. The specific oxygen uptake rate by organism and the oxygen transfer coefficients of liquid-films which were assumed to exist around air bubbles and cells respectively, were estimated and those values were compared. The experimental values of k_La were compared with the predicted values of k_La obtained by using the correlations for k_L and a presented in our previous work.

• 社団法人日本生物工学会の論文
• 1966-12-25

著者

• 三浦 喜温

  Department Of Pharmaceutical Engineering Chemistry Faculty Of Pharmaceutical Sciences Osaka Universi

• 広田 昇治

  Himeji Institute of Technology

関連論文

• 充填塔における化学反応吸収(反応率の大きい場合)
• Transfer of Oxygen Supplied by Aeration in Submerged Fermentation
• Anticoagulant Acivity of Immobilized Thrombomodulin

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