ビタミンB_1欠乏シロネズミ肝のTransketolaseおよび脂質代謝におよぼす飼料組成の影響

概要

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Liver transketolase activity, liver total lipid content, and plasma NEFA level were measured in the rats fed with thiamine-deficient diet of standard or high fat content and of low or high protein content. The transketolase activities were significantly low in thiamine-deficient rats, but were almost normal in the rats fed with thiamine-supplemented diets or when the rats were put under starvation. The activities recovered to normal when the thiaminedeficient rats received thiamine, although the lowest recovery rate was seen when the rats had been fed with low protein, thiamine-deficient diet. Liver total lipid contents decreased, and plasma NEFA levels increased only in the late stage of thiamine deficiency. Injection of thiamine was followed by marked increase in the lipid, and indefinite change in NEFA levels. The roles of fat and protein in the metabolism of thiamine-deficient condition were discussed. (Received June 16,1970)
日本ビタミン学会の論文
1970-09-25