Graph Modeling of Metabolism

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概要

• 論文の詳細を見る

• Systematic understanding of biological phenomena is necessary for its modeling. However, traditional analyses with differential equations often ended in an imitation of observed laboratory results, and too much effort was spent in reproducing the known quantitative data. What is more important is a strategy to computationally reconstruct the systematic aspect of biology. The paper introduces a strategy to represent metabolism using a graph. Its key idea is simple: to model metabolism only with enzymatic reactions and with chemical structures at the atomic level. The strategy was realized as AMR system, and was tested for a simple tracer experiment around TCA cycle.

• 社団法人人工知能学会の論文
• 2000-07-01

著者

• Arita Masanori

  Electrotechnical Laboratory

関連論文

• Graph Modeling of Metabolism

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