機能的遊離筋肉移植に対する治療的電気刺激の効果の実験的検討

概要

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Functioning muscle transplantation (FMT) can provide useful in extremity reconstruction, but the motor nerve fascicles available for reinnervation are often insufficient. The purpose of this study was to investigate the effect of therapeutic electrical stimulation (TES) following FMT when there were insufficient motor nerve fascicles available. The right musculocutaneous nerve, which innervates the biceps brachia in a beagle dog, was used. The motor branch of the nerve was severed 1 cm proximal to the neuromuscular junction. The proximal nerve stump contained several fascicles. Half of these fascicles were shortening by 1 cm then ligated. The remainder was sutured to the distal stump. An electrode of stimulator was placed at the neuromuscular junction of the biceps brachia. Half of the dogs received TES for eight weeks, while the other half (control group) received no stimulation. In both groups, power and endurance of the muscle were measured. After eight weeks, the power and endurance of the muscle in the dogs receiving the TES were greater than for the control group. These results suggest that TES following FMT increases the power and the endurance of the reinnervated muscle.
2003-12-31