心房中隔及び其の周邊に於ける刺戟傳播状態.特に洞田原系に就いての實驗的研究(第1報) : 心房中隔表面の刺戟傳播状態について

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Since the sinus node was discovered, two different theories were discussed on the atrial stimulus conduction, namely one through the specific heart muscle, and the other, radiation spread through the proper muscle. And by the theory which recognized the stimulus conduction system between the sinus node and atrio-ventricular node, it's existence was surmized in the interatrial septum.Then, in this paper, the spread of the excitation on the surface of the interatrial septum was studied.The isolated dog's hearts were perfused by Langendorff's technique and placed in the great vessel. As perfused solution, the defibrinated blood was added to Lock's solution. The E. C. G. was recorded simultaneously by means of the direct unipolar leads with the different electrodes, one at the interatrial septum and the other at the sinus node in the superior vena cava and the indifferent electrode at the great vessel.The excitation arrival was measured at many points of the interatrial septum. The time arrival in the intrinsic deflection was at the point it crossed the zero-line by "chain doublet theory" which Prof. Maekawa advocated.The summary and conclusion of this study are as follows : The electrical leads were performed at the right surface of interatrial septum in 10 cases and at the left surface of interatrial septum in 6 cases. 1) The excitation spreaded earliest at times around the orifice of the superior vena cava and next from the cranial area to the caudal area of the Torus Loweri and then to the inferior vena cava side on the atrial septum, neighbourhood of the atrio-ventricular node and coronary sinus. 2) The arrival of the excitation at the neighbourhood of the atrioventricular node was delayed commonly as compared with it at the other area of the right side of the interatrial septum, but it was found that the excitation at a point arrived earlier than the other point on the neighbourhood of the atrioventricular node in some cases. 3) The excitation at the left side of the interatrial septum arrived in various ways but generally it was thought that the excitation were caused along the muscle bundle which was related by Osawa from the anteriorsuperior area of the interatrial septum to the other areas. 4) By the results of this study, it could not be confirmed that the specific pathways were between the sinus node and atrio-ventricular node, and also the excitation was diffusive.
社団法人日本循環器学会の論文
1959-08-20

心房中隔及び其の周邊に於ける刺戟傳播状態.特に洞田原系に就いての實驗的研究(第1報) : 心房中隔表面の刺戟傳播状態について

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