Effects of pH and Glucose Concentration on Production of Rifamycin Oxidase
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概要
- 論文の詳細を見る
As part of a study on production of rifamycin oxidase using a strain of Humicola sp.(ATCC 20620), the effects of pH and glucose concentration in the fermentation medium on cell growth and enzyme productivity were investigated. Although it was apparent that enzyme production was not repressed by high glucose concentration up to 60 g glucose/l of culture broth, more precise pH control was necessary to maintain the enzyme production at a desired level when a high sugar concentration was to be employed in an industrial scale operation. The maximum specific growth rate was found to be 0.24 h^<-1> with a constant pH (pH=7.0), while it was only 0.19h^<-1> without ph control. Maintaining the pH at 8.0 during the fermentation was considered most favorable for enzyme productivity.
- 公益社団法人日本生物工学会の論文
- 1984-04-25
著者
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Park M.j.
Division Of Biological Science And Engineering The Korea Advanced Institute Science And Technology
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KIM K.E.
Biochemical Engineering Laboratory, Department of Chemical Technology, Seoul National University
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CHOI Y.C.
Biochemical Engineering Laboratory, Department of Chemical Technology, Seoul National Unviersity
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HAN H.M.
Division of Biological Science and Engineering, The Korea Advanced Institute Science and Technology
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PARK H.Y.
Division of Biological Science and Engineering, The Korea Advanced Institute Science and Technology
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Choi Y.c.
Biochemical Engineering Laboratory Department Of Chemical Technology Seoul National Unviersity
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Park H.y.
Division Of Biological Science And Engineering The Korea Advanced Institute Science And Technology
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Kim K.e.
Biochemical Engineering Laboratory Department Of Chemical Technology Seoul National University