Loss of ε-Aminocaproate Metabolism in Corynebacterium aurantiacum
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概要
- 論文の詳細を見る
Corynebacterium aurantiacum B-2 is characterized by its ability to grow on ε-caprolactam and cyclic oligomers of ε-aminocaproic acid (ACA) larger than the trimer as the sole source of carbon and nitrogen. Slow growth of B-2 colonies on an ACA cyclic tetramer agar medium kept in a cold room (12±3℃) for 5 weeks resulted in production, with a 32% frequency, of cells of a metabolic variant which could not grow on the cyclic tetramer, ε-caprolactam or ACA. This variant strain retained hydrolysis activities toward the cyclic tetramer, the linear dimer and ε-caprolactam, but lost the ACA transaminase activity. This high rate of curing of the ACA metabolism and the lack of reversion to the original characteristics suggest that the gene for ACA transaminase may be carried by a plasmid.
- 公益社団法人日本生物工学会の論文
- 1982-10-25
著者
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Teramura Yasuhiro
(present Address)division Of Biology Research Institute For Atomic Energy Osaka City University
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FUKUMURA TAKASHI
Department of Biology, Faculty of Science, Osaka City University
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Fukumura Takashi
Department Of Biology Faculty Of Science Osaka City University