Metabolic Improvements and Use of Inexpensive Carbon Sources in Microbial Production of Polyhydroxyalkanoates(BIOCHEMICAL ENGINEERING)
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概要
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This paper deals with the microbial production of polyhydroxyalkanoates (PHAs), biodegradable thermoplastics which perform excellently as a material, from inexpensive renewable carbon sources. To date, with the help of genetic engineering techniques, it has become possible to design several types of PHAs with different compositions and to enhance the productivities of PHAs. In addition, molecular breeding of PHA biosynthesis enzymes has been demonstrated to improve polymer production. Mutant PHA synthases generated by an in vitro evolution technique have allowed the enhanced production and quality alteration of PHAs. Furthermore, use of inexpensive renewable carbon sources, such as plant oils, waste materials, and carbon dioxide, would be a key for a reduction in PHA production cost.
- 公益社団法人日本生物工学会の論文
- 2002-12-25
著者
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TSUGE TAKEHARU
Department of Food Science and Technology, Faculty of Agriculture, Kyushu University
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Tsuge Takeharu
Department Of Innovative And Engineered Materials Tokyo Institute Of Technology
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