Study on the Pathogenesis of Nephritis : (With Special Reference to Autoradiography) Part I Experimental Studies

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概要

• 論文の詳細を見る

• The pathogenesis of nephritis was investigated in this paper, especially, by means of Autoradiograph. 3^H-Thymidine, a precursor of DNA, was given rats, and Auto-radiograph was prepared in vivo. The proliferative change of kidney was pararell to numbers of labelled cellular component, because uptake of 3^H-Thymidine was premise of mitosis. As the experimental parameter, three groups including Masugi Nephritis, heterologous serum nephritis and CCl_4 induced nephropathy of rats were used. An attempt has been made to clarify time lag between histological findings and proliferative lesions recognized as "Labelling Index" on autoradiogram. The autoradiographic technic proves a very effective tool to detect proliferative changes of kidney, which was unable to be observed by conventional microscopic examination.

• 社団法人日本循環器学会の論文
• 1970-12-31

著者

• Ohkura Takanobu

  Nagoya University School Of Medicine 3rd Department Of Internal Medicine

関連論文

• Study on the Pathogenesis of Nephritis : (With Special Reference to Autoradiography) Part II Clinical Studies
• Study on the Pathogenesis of Nephritis : (With Special Reference to Autoradiography) Part I Experimental Studies

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