Clinical and Experimental Studies on Acid Adenosine Triphosphatase, with Special Reference to Lysosomes and Isozyme

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概要

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• The origin of serum acid ATPase was investigated. Lysosomes were the most likely origins of the enzyme, although direct evidence is not yet obtained. Acid ATPase levels in sera from patients with various diseases were high. Several interesting cases in regard to the enzyme were presented and discussed from the lysosomal point of view. Presence of acid ATPase isozyme in various organs and serum was evident. Human serum acid ATPase activity was electrophoretically associated with α and β-globulins and showed a minor peak with larger molecule and a major peak with smaller molecule (approx. 9×10^4) on Sephadex G-200. Human serum acid ATPase activity was resolved into at least three peaks by DEAE-cellulose column chromatography.

• 社団法人日本循環器学会の論文
• 1968-04-20

著者

• Kira Jun

  The Third Division Department Of Internal Medicine School Of Medicine Kyoto University

関連論文

• Clinical and Experimental Studies on Acid Adenosine Triphosphatase, with Special Reference to Lysosomes and Isozyme

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