虚血性心疾患における脂血症の類型,コレステロール及び中性脂肪濃度の観点から
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The study of arteriosclerosis in relation to hyperlipemia has been a subject of many clinical investigators, and considerable amount of knowledge has been accumulated through their works. And some classifications of hyperlipemia have been presented on the basis of disordered lipid metabolism. We have performed a clinical observation on arteriosclerosis for the recent several years, analyzing the serum lipids and classifying lipemia into several categories according to the serum cholesterol and triglyceride levels. This time, my aim is to investigate the lipid pattern which is more characteristic for ischemic heart disease and to compare this result to the reports from other countries. Material and Methods Hospitalized male and female patients with various diseases, aged 40 years or more, were studied, except the subjects with such disease to be apt to accompany serum lipid disorder as renal disease, diabetes mellituis, and hepatobiliary and endocrinological disorders. All subjects were divided into three groups as follows: l) One hundred and seventy-three cases of ischemic heart disease diagnosed by the observation on the abnormal ST segments and T waves on electrocardiograms according to the Minnesota code (39 cases of myocardial infarction were included). 2) Fifty cases of cerebral vascular lesion. 3) Three hundred and thirty-seven cases of non-ischemic control subjects (cerebral vascular lesions were not included). The subjects were taking the foods having 2300-2350 calories on the basis of 80 g of proteins, 45 g of fats, and 400 g of carbohydrates per day. No drugs which significantly influence on serum lipids were administered during the experiment. The fasting blood samples were obtained in the early morning 1 2 hours or more after the last meal. Serum cholesterol concentration was estimated by ZURKOWSKl'S method with a little modification, and serum triglyceride concentration by LAURELL'S method.
- 社団法人日本循環器学会の論文
- 1970-01-20
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