RELATION BETWEEN MIXED VENOUS BLOOD OXYGEN SATURATION AND CARDIAC PUMPING FUNCTION AT THE ACUTE PHASE OF MYOCARDIAL INFARCTION

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In this study, we monitored changes in the mixed venous blood oxygen saturation (Sv^^-O_2) level of 45 patients with acute myocardial infarction and compared these results to the traditional parameters. The Sv^^-O_2 level was found to correlate well with the clinical course of patients and their hemodynamic conditions. The mean Sv^^-O_2 level of the group having congestive heart failure (53.3±8.4%) was found to be statistically lower than those without (69.8±5.6). Furthermore, patients whose Sv^^-O_2 level was lower than 60% were found to be at greater risk for heart failure and a very high mortality rate. Patients were classified into four subsets according to Forrester's hemodynamic classification; their Sv^^-O_2 levels were 70.7±4.1% (I: 23 cases), 54.7±6.9% (II: 8 cases), 55.8±9.4% (III:10 cases), and 47.0±8.0 (IV: 4 cases), respectively. A reverse relationship between pulmonary capillary wedge pressure and Sv^^-O_2 having a correlation coefficient of r=-0.64 was observed, and a logarithmic curvilinear relation between cardiac index ~ Sv^^-O_2, stroke volume index ~ Sv^^-O_2, and left ventricular stroke work index ~ Sv^^-O_2 was also evident. When the decrease in the Sv^^-O_2 level was more than 5%, it always showed a significant decrease in the cardiac index. This study suggested that continuous monitoring of the Sv^^-O_2 level revealed simultaneous changes in the hemodynamic state, which lead to the assistance and aid for treating patients with critical conditions of acute myocardial infarction. In such circumstances, it was noted that the Sv^^-O_2 level should be maintained above 60% in order to stabilize the hemodynamic state.
社団法人日本循環器学会の論文
1989-12-20

RELATION BETWEEN MIXED VENOUS BLOOD OXYGEN SATURATION AND CARDIAC PUMPING FUNCTION AT THE ACUTE PHASE OF MYOCARDIAL INFARCTION

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