TEMPORAL FOURIER TRANSFORM OF DIGITAL ANGIOGRAMS FOR LEFT VENTRICULAR REGIONAL WALL MOTION ANALYSIS
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概要
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To determine whether or not the first harmonic of a temporal Fourier transform, applied pixel-by-pixel on time-intensity curves, can detect the subtle wall motion abnormalities due to ischemia, 6 dogs were instrumented with a micromanometer in the left ventricles, a hydraulic cuff occlluder around the circumflex coronary artery, and sonomicrometers on the inferior (ischemic) and anterior (non-ischemic) walls. Left ventricular images, obtained after contrast injection via the pulmonary artery, were compared with dimension signals in control and 3 progressive levels of coronary stenosis (Stenosis I, II and III). Normalized, digital functional images (512 × 512 matrix, 256 shades of gray/pixel) were divided into anterior, apical, and inferior areas to acquire regional mean phase (degrees) and amplitude (intensity units) values. After inducing stenosis, phase in ischemic region significantly increased at all 3 levels of stenosis, whereas amplitude significantly decreased at Stenosis II and III. However, amplitude images showed clearly the topographic site of ischemia. There was a progressive increase in phase and decrease in amplitude in ischemic areas as the percent wall thickening (%WTh) fell (phase vs. %WTh: r = -0.55, p 0.005; amplitude vs. %WTh: r = 0.71, p 0.001). Heart rate and peak systolic pressure showed no significant changes during stenoses. We conclude that quantitative functional images, generated from a temporal Fourier transform, are sensitive to the detection of left ventricular regional wall motion abnormalities during mild, moderate, and severe degrees of ischemia.
- 社団法人日本循環器学会の論文
- 1988-07-20
著者
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Widmann Thomas
Division Of Cardiology Department Of Medicine School Of Medicine University Of California
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Lee Jong
Division Of Hematology Department Of Internal Medicine St. Mary's Hospital College Of Medicine
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Lee Jong
Division Of Cardiology Department Of Medicine School Of Medicine University Of California
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KATAYAMA KAZUHIRO
Division of cardiology, Department of Medicine, School of Medicine, University of California
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GUTH BRIAN
Division of cardiology, Department of Medicine, School of Medicine, University of California
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SEITELBERGER RAINALD
Division of cardiology, Department of Medicine, School of Medicine, University of California
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PETERSON KIRK
Division of cardiology, Department of Medicine, School of Medicine, University of California
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Guth Brian
Division Of Cardiology Department Of Medicine School Of Medicine University Of California
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Peterson Kirk
Division Of Cardiology Department Of Medicine School Of Medicine University Of California
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Katayama Kazuhiro
Division Of Cardiology Department Of Medicine School Of Medicine University Of California
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Seitelberger Rainald
Division Of Cardiology Department Of Medicine School Of Medicine University Of California
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Lee Jong
Division Of Cardiology Department Of Internal Medicine Uijeongbu St. Mary's Hospital
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