Physiological Factors of Atrial Natriuretic Polypeptide Release and Its Neural Regulation in Conscious Dogs : SYMPOSIUM ON ATRIAL NATRIURETIC POLYPEPTIDE (ANP): Basic and Clinical Research : 51th Annual Scientific Session of the Japanese Circulation Socie
スポンサーリンク
概要
- 論文の詳細を見る
We have examined physiological factors in atrial natriuretic polypeptide (ANP) release and whether or not the cardiac nerves control release of ANP. Two possible factors were tested, an increase in plasma sodium level (PNa) and an increase in atrial pressure. Injection of 1.0 or 2.0 mEq/kg of sodium ions elevated PNa by 5.3±0.3 or 7.3±0.4 mEq/L, respectively, but plasma ANP level (PANP) did not change. Infusion of 18 ml/kg of 3% Dextran-40 over 5 min increased mean left atrial pressure (MLAP) by 7.6±0.9 mmHg. PANP increased from 206±17 pg/ml to 260±25 pg/ml, which was not significant. PANP, corrected for hemodilution, significantly increased to 348±34 pg/ml. These results suggest that PNa increase does not promote ANP release, but that an atrial pressure increase does. This transient volume load did not induce full response of the ANP releasing system. A prolonged volume load for 45 min increased corrected PANP to 435±73 pg/ml. A close linear correlation was found between the increases in MLAP and PANP. These facts indicate that prolonged volume expansion is necessary to induce full response of the ANP releasing system. Complete cardiac denervation did not affect the tonic level of plasma ANP, volume expansion-induced increase in PANP, or the sensitivity of the ANP releasing system. Thus we conclude that the cardiac nerves do not control ANP release caused by volume expansion.
- 社団法人日本循環器学会の論文
- 1988-12-20
著者
-
Miyata Atsuro
Department Of Pharmacology Kagoshima University Graduate School Of Medical And Dental Sciences
-
Miyata Atsuro
Department Of Biochemistry Miyazaki Medical College
-
NISHIDA Yasuhiro
Department of Ophthalmology, Shiga University of Medical Science
-
Nishida Yasuhiro
Department Of Ophthalmology Shiga University Of Medical Science
-
Nishida Yasuhiro
Department Of Physiology Kagawa Medical School
-
Morita Hironobu
Department Of Physiology Gifu University School Of Medicine
-
Maeta H
Kagawa Medical Univ. Kagawa Jpn
-
Hosomi Hiroshi
Department Of Physiology Kagawa Medical School
-
Hosomi Hiroshi
Department Of Physiology Kagawa Medical College
-
Morita Hironobu
Department Of Physiology Kagawa Medical School
-
Morita Hironobu
Department Of Physiology Gifu University Graduate School Of Medicine
-
Maeta Hajime
First Department Of Surgery Kagawa Medical School
関連論文
- A Muscle Transposition Procedure for Abducens Palsy, in Which the Halves of the Vertical Rectus Muscle Bellies Are Sutured Onto the Sclera
- An Automated Measuring System for Fundus Perimetry
- VOLUME MEASUREMENT OF HORIZONTAL EXTRAOCULAR MUSCLES WITH MAGNETIC RESONANCE IMAGING
- -91- NEURAL AND HUMORAL CONTROL OF THE PULMONARY VASCULAR BED AND THE ROLE OF α_1-RECEPTOR : Pulmonary Circulation, Papillary Circulation : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- -420- MOLECULAR FORMS OF PLASMA AND RIGHT AURICLE ATRIAL NATRIURETIC POLYPEPTIDE IN PATIENTS WITH CARDIOVASCULAR DISEASE
- D-Allose has a strong suppressive effect against ischemia/reperfusion injury : a comparative study with allopurinol and superoxide dismutase
- Changes in Arterial and Portal Perfusion in Embolized and Nonembolized Hepatic Lobes After Portal Vein Embolization Evaluated by Helical Computed Tomography
- Increase in Portal Blood Interleukin-6 Soon After the Commencement of Digestive Surgery
- Effects of Left Intraatrial Infusion of Prostaglandin E_1 After Open-Heart Surgery
- Role of Endogenous Opioids and Central Opioid Receptors in Cerebral Cortical Blood Flow Autoregulation
- TONIC REGULATION OF RENAL CIRCULATION BY BAROREFLEX SYSTEM : Circulation Control : V : 48 Annual Scientific Meeting, Japanese Circulation Society
- -478- TEMPORAL AND SPATIAL INTERACTIONS BETWEEN THE CAROTID SINUS AND VAGALLY MEDIATED BAROREFLEXES IN DOGS
- -477- DEPRESSED BAROREFLEX CONTROL OF RENAL NERVE ACTIVITY IN CONSCIOUS WHHL RABBITS
- -451- EFFECTS OF PHENYLEPHRINE AND NALOXONE ON RENAL NERVE ACTIVITY DURING HEMORRHAGIC HYPOTENSION
- -103- EFFECTS OF LOW CEREBRAL PERFUSION PRESSURE ON THE BARORECERTOR REFLEX SYSTEM : Pulmonary Circulation, Papillary Circulation : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- A Simple Muscle Transposition Procedure for Abducens Palsy Without Tenotomy or Splitting Muscles
- Change in Intrathoracic Pressure in Rats with Spontaneous and Controlled Ventilation during Microgravity by Parabolic Flight
- Cerebral hemodynamics during microgravity
- Relationship between Transmural Pressure and Aortic Diameter during Free Drop-Induced Microgravity in Anesthetized Rats
- Effects of pCO_2 on the CSF Turnover Rate in Rats Monitored by Gd-DTPA Enhanced T_1-Weighted Magnetic Resonance Imaging
- Acute responses of renal nerve activity to microgravity induced by free drop in anesthetized rats
- Afferent Mechanism of Ranal Sympathetic Nerve Activity Shutdown Induced by Short Period of Microgravity
- Neuromuscular Electrical Stimulation and an Ottoman-Type Seat Effectively Improve Popliteal Venous Flow in a Sitting Position
- Extent of pathologic invasion of the inferior vena cava in resected liver cancer compared with possible caval invasion diagnosed by preoperative images
- I2-1 Dose-dependent suppression of neutrophil infiltration by D-allose in ischemic reperfused rat liver
- Cellular localization of CD44 correlates with cell proliferation and liver metastasis in colon cancer
- Modified hepatoduodenal ligamentectomy for advanced carcinoma of the biliary tract : The importance of preservation of the replaced left hepatic artery
- Treatment of Recurrent Hepatocellular Carcinoma by Hepatectomy with Right and Middle Hepatic Vein Reconstruction Using Total Vascular Exclusion with Extracorporeal Bypass and Hypothermic Hepatic Perfusion:Report of a Case
- Hepatic Protein Synthesis in the Regenerating Rat Liver After Hepatopancreatectomy
- Effect of Preoperative Portal Vein Embolization on Major Hepatectomy for Advanced - Stage Hepatocellular Carcinomas in Injured Livers: A Preliminary Report
- Curative resection for malignant glucagonoma
- Resection of the head of the pancreas in three patients with anomalous arrangement or occlusive diseases of the major abdominal visceral arteries
- Microarray Analysis of Laser Capture Microdissected Substantia Nigra Pars Compacta after a Single Administration of MPTP in Common Marmosets
- Physiological Factors of Atrial Natriuretic Polypeptide Release and Its Neural Regulation in Conscious Dogs : SYMPOSIUM ON ATRIAL NATRIURETIC POLYPEPTIDE (ANP): Basic and Clinical Research : 51th Annual Scientific Session of the Japanese Circulation Socie
- Protective effects of D-allose against ischemia reperfusion injury of the rat liver
- Effects of High NaCl Diet on Arterial Pressure in Sprague-Dawley Rats with Hepatic and Sinoaortic Denervation
- Cerebral Circulation during Acute Microgravity Induced by Free Drop in Anesthetized Rats
- -347- THE FUNCTIONAL RANGES OF AUTOREGULATION OF RENAL BLOOD FLOW IN DOG
- -332-EFFECTS OF BRAIN NATRIURETIC PEPTIDE ON BARORECEPTOR REFLEX SYSTEM IN DOGS : Atrial Natriuretic Polypeptide : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure
- Skin Blood Flow with Elastic Compressive Extravehicular Activity Space Suit
- R-R Interval Variability with Lower Body Positive Pressure Assessed by Wavelet Packet Transform
- Development of a Fistula Between an Internal Mammary Artery Graft and the Pulmonary Vasculature Following Coronary Artery Bypass Grafting : Report of a Case
- Extrapancreatic lymphoepithelial cyst of the pancreas
- The effects of intraportal administration of prostaglandin E_1 on liver ischemia and hepatectomy in rats
- Partial Endografting of Prosthetic Vessels in Internal Shunts for Hemodialysis Access to Allow Early Puncture
- Lateral diffusion of manganese in the rat brain determined by T_1 relaxation time measured by ^1H MRI
- Role of Hepatic Receptors in Controlling Body Fluid Homeostasis
- A case of extraocular muscle swelling due to IgG4-related sclerosing disease
- Negative feedforward control of body fluid homeostasis by hepatorenal reflex
- Baro-excited neurons in the caudal ventrolateral medulla (CVLM) recorded using the whole-cell patch-clamp technique
- Survey of microphthalmia in Japan
- Long-term blood pressure control : is there a set-point in the brain?