THE CLINICAL TRIAL OF A NEW HYPOTENSIVE AGENT,"FUSARIC ACID (5-BUTYLPICOLINIC ACID)": THE PRELIMINARY REPORT

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概要

• 論文の詳細を見る

• Fusaric acid (5-butylpicolinic acid) was found to be a potent inhibitor of dopamine β-hydroxylase in vitro and in vivo. The depression of the levels of endogenous norepinephrine was demonstrated in brain, heart, spleen and adrenal glands of the rat. This compound showed a consistent hypotensive effect in experimental animals, also. This study was conducted to prove the hypotensive activity of this compound in humans, for the purpose of testing whether or not this compound could be a unique antihypertensive drug in clinical medicine.

• 社団法人日本循環器学会の論文
• 1971-04-20

著者

• Terasawa Fujio

  Fusarium Species Department Of Agricultural Chemistry University Of Hokkaido

• Kameyama Masakuni

  Fusarium Species Department Of Agricultural Chemistry University Of Hokkaido

関連論文

• THE CLINICAL TRIAL OF A NEW HYPOTENSIVE AGENT,"FUSARIC ACID (5-BUTYLPICOLINIC ACID)": THE PRELIMINARY REPORT

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