Experimental Hypertension Metabolism and the Genesis of Hypertension (I)

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概要

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• 1) The mild to moderate degree of experimental hypertension was induced by consecutive injection of 2.4 dinitrophenol and monoiodoacetate to the albino rats. It has been demonstrated that hypertension could be induced by the disturbed processes of metabolism. 2) With DNP group, the serum cholesterol tended to decrease, whereas with MIA group it remained practically unchanged. 3) With regard to the serum electrolytes, the serum Na in both groups failed to show significant alteration, whereas the serum K in both groups tended to decrease. 4) Urinary protein in both groups were detectable, though slightly, sometime around the 15th day of the initiation of injection. Urinary quantities remained the same. No changes in Na and K in the urine of DNP group to be seen, whereas in MIA group the excretion of K tended to be increased in quantity. 5) Pathological observation of the renal tissues of both groups revealed hardly any changes nor in the other organs. 6) The present experimental hypertension has made clear that it is unrelated to renal disturbance.

• 社団法人日本循環器学会の論文
• 1966-11-20

著者

• Abe Tadayoshi

  The 1st Department Of Internal Medicine Kobe Medical College

• ABE T.

  The 1st Division, Dept. of Inter. med., Kobe Medical College

関連論文

• Experimental Hypertension Metabolism and the Genesis of Hypertension (I)
• Experimental Hypertension : Metabalism and the Genesis of Hypertension(III)
• Experimental Hypertension Metabolism and the Genesis of Hypertension (II)
• 167) Statistical and Experimental Studies on Essential Hypertension(Proceedings of the 24th Annual Meeting, The Japanese Circulation Society [Part III])
• Studies on the Acute Pulmonary Edema in Mitral Stenosis(Proceedings of the 24th Annual Meeting The Japanese Circulation Society [Part II])

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