A STUDY OF HYPERTENSION THE EFFECTS OF ANGIOTENSIN II ON THE MAO ACTIVITY AND ROLES OF CALCIUM ION ON THE CATECHOLAMINE CONTENTS IN THE RAT HYPOTHALAMUS AND STRIATUM
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概要
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The artificial CSF perfusions have been made to detect some roles of Ca^<++> in the brain catecholamines and angiotensin II, using hypothalamus and striatum. Rats were given perfusions through the left lateral ventricle to the third ventricle. Synthetic angiotensin II was added 3 minutes before the brain was frozen. Then catecholamines and MAO activity were determined. Angiotensin II reduced markedly noradrenalin in the hypothalamus, although dopamine and noradrenalin in the striatum and dopamine in the hypothalamus remained unchanged, moreover it caused a marked reduction of the MAO activity in the hypothalamus, but not in the striatum. The effect of angiotensin II on the hypothalamus is reduced when the Ca^<++> concentration in tissue is low.
- 社団法人日本循環器学会の論文
- 1972-06-20
著者
関連論文
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- DISCHARGE UNITS (DU) OF NUCLEUS TRACTUS SOLITARII (NTS) IN SPONTANEOUSLY HYPERTENSIVE RAT (SHR) : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Hypertension
- A STUDY OF HYPERTENSION THE EFFECTS OF ANGIOTENSIN II ON THE MAO ACTIVITY AND ROLES OF CALCIUM ION ON THE CATECHOLAMINE CONTENTS IN THE RAT HYPOTHALAMUS AND STRIATUM