Experimental Studies on the Pathogenesis Of Arteriosclerosis With Special Reference to Blood Coagulation

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概要

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• It is now generally accepted that lipemia has a close relationship to the pathogenesis of arteriosclerosis, and blood coagulation has been reported to be accelerated by alimentary lipemia. Recently the atherogenic factor of lipemia has been discussed with reference to this hypercoagulability induced by lipemia. This paper presented the experimental investigations on the influence of hypercoagulability in the pathogenesis of the arteriosclerosis. Authors found that blood coagulability was markedly accelerated in vivo after the injection of celite, which was demonstrated in the decrease of whole blood clotting time, the increase of serum thromboplastic factor and the decrease of some blood clotting factors which were asssumed to be due to the increased consumption of them in vivo. The atherosclerotic changes in aorta and pulmonary arteries produced with cholesterol feeding were accelerated by this experimentally induced hypercoagulability. From these results authors considered that hypercoagulability of blood probably plays the primary role in the pathogenesis of arteriosclerosis.

• 社団法人日本循環器学会の論文
• 1962-06-20

著者

• Furuta Seiichi

  Department Of Internal Medicine Faculty Of Medicine Shinshu-university

• MATSUOKA MATSUZO

  Department of Internal Medicine, Faculty of Medicine, Shinshu-University

• USHIMARU TOSHIO

  Department of Internal Medicine, Faculty of Medicine, Shinshu-University

• Ushimaru Toshio

  Department Of Internal Medicine Faculty Of Medicine Shinshu-university

• Matsuoka Matsuzo

  Department Of Internal Medicine Faculty Of Medicine Shinshu-university

• MATSUOKA M.

  Department of Hygiene and Public Health I, Tokyo Women's Medical University

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