上腕動脈脈波に関する臨床的研究
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概要
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The elasticity of the vascular wall has been the subject of many studies either with surgical or without surgical methods. The present author attempted to measure the elasticity of the arterial wall from the pulse wave curve recordable at the brachial artery and with a set of rather bold assumptions. Namely, the author assumed the arterial wall as a simple physical system with elasticity. Under this assumption the following equation will apply to the movement of the arterial wall: md^2x/dt^2=-Kx x=Sin ωt ω=2π/T T=2π√<m/K> where m : unit mass of the arterial wall tissue x : distance of the dislocation of a fixed point on the arterial wall vertical to the axis of the artery k : coefficient of elasticity T : period of sine wave The measurement of T will then allow the estimation of K, the coefficient of elasticity. Since, on the other hand, the velocity of the pulse wave propagation is related to the elasticity coefficient as follows : V∝√<p/K> there is another method of estimating the elasticity coefficient of the arterial wall. Methods Materials used consisted of three groups, (a) normal group, (b) arteriosclerotic group and (c) non-arteriosclerotic group consisting of cases with juvenile hypertension, nephritis and cardiac disease. The pulse wave was measured from the brachial artery by such arrangements that each pulse wave caused a corresponding change in the electrical capacity of the system which was presented to a condense microphone. At the same time, occlusion was applied 20cm distal to the point of the pulse wave recording by tighteing a vinyl-covered rubber band around the arm in order to measure the period of the reflected wave component (will be accentuated by occlusion) and measure the occlusion. Following this, the injection of TEAB or noradrenalin was performed and Pulse waves were recorded before and after injection (in this case, too, with and without occlusion). Throughout the course of these tests, simultaneous electrocardiograms were recorded by the third limb lead. The duration of time intervening between the R wave of electrocardiogram and the origin of ascending limb of the pulse wave gave the pulse wave arrival time. In this way the percentage change in pulse ware arrival time due to occlusion was also determined.
- 1961-01-15