THE HEMODYNAMICS OF EARLY STAGES OF SPONTANEOUS HYPERTENSION IN RATS PART I : MALE STUDY
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概要
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Male spontaneously hypertensive rats (SHR) were tested for the cardiac output and organ blood flows at the age 30, 40, 50, 60, 90 and 180 days. The results showed that during the course of developing hypertension in SHR the cardiac output was not elevated. During the prehypertensive period, total peripheral resistance was not elevated, but systolic blood pressure was higher in SHR than in normotensive rats. Increased contractility of the myocardium in SHR was considered to be involved in the pathogenesis of hypertension. Decreased kidney blood flow in SHR after 90 days of age might be related to the high incidence of nephrosclerosis in 180 days old male SHR.
- 社団法人日本循環器学会の論文
- 1974-12-20
著者
関連論文
- THE HEMODYNAMICS IN FEMALE SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
- THE HEMODYNAMICS OF EARLY STAGES OF SPONTANEOUS HYPERTENSION IN RATS PART I : MALE STUDY
- THE HEMODYNAMICS OF EARLY STAGES OF SPONTANEOUS HYPERTENSION IN RATS PART II : FEMALE STUDY