Immunological Aspects of Aortitis Syndrome

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概要

• 論文の詳細を見る

• 1. Anti-aortic antibodies were frequently detected from the sera of patients with aortitis syndrome. 2. Aortic antigens were demonstrated to exist mainly in the media. The antigenicity was inactivated by collagenase, trypsin and pepsin, but not by DNase-I. Analyses of aortic antigens were also made by ultracentrifugation and column chromatography. 3. Experimental arteritis could be produced in animals by isologous active immunization and by heterologous passive immunization. 4. From these results, participation of antigen-antibody reaction in the development of the disease has been speculated. Possible role of streptococcal infection as one of the trigger mechanisms in antibody production has been suggested in combination with evidences indicating hypersensitivity of the patients to infections.

• 社団法人日本循環器学会の論文
• 1975-05-20

著者

• Ito Iwao

  The 2nd Department Of Internal Medicine Faculty Of Medicine University Of Tokyo

• Saito Yoshimi

  The 2nd Department Of Internal Medicine Faculty Of Medicine University Of Tokyo

• NONAKA YASUNOBU

  The 2nd Department of Internal Medicine, Faculty of Medicine, University of Tokyo

• Nonaka Yasunobu

  The 2nd Department Of Internal Medicine Faculty Of Medicine University Of Tokyo

関連論文

• Immunological Aspects of Aortitis Syndrome

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