A STUDY OF CORONARY CIRCULATION IN EXPERIMENTAL AORTIC INSUFFICIENCY WITH SPECIAL REFERENCE TO PHASIC CORONARY FLOW PATTERN

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概要

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• Systemic and coronary hemodynamic changes, especially phasic coronary flow pattern changes, were studied in experimental aortic insufficiency dogs. Aortic insufficiency severe enough to lower the mean aortic pressure resulted in an increase in aortic total flow and a decrease in aortic foward flow. Aortic pulse pressure always widened while no changes of systolic aortic pressure occurred. The mean coronary blood flow was increased significantly above control condition with the shift of normal diastolic flow to systole in mild and moderate cases, but was decreased in severe cases showing prominent backward coronary flow during diastole. The phasic coronary flow pattern changes had the close correlationship to the aortic pressure and the aortic regurgitant flow in the experimental aortic insufficiency. The mechanism of angina pectoris in aortic insufficiency was discussed from the standpoint of the phasic coronary flow.

• 社団法人日本循環器学会の論文
• 1973-05-20

著者

• Mizutani Tetsuo

  The First Department Of Internal Medicine School Of Medicine Kobe University

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• A STUDY OF CORONARY CIRCULATION IN EXPERIMENTAL AORTIC INSUFFICIENCY WITH SPECIAL REFERENCE TO PHASIC CORONARY FLOW PATTERN

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