AUGMENTATION OF PRESSOR RESPONSE TO EXOGENOUS RENIN IN RATS WITH ACUTE MERCURIC CHLORIDE INTOXICATION : FAILURE TO DEMONSTRATE RENIN ACTIVATING PRINCIPLE (S) IN PLASMA

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概要

• 論文の詳細を見る

• Velocity of angiotensin formation has been studied using normal rat plasma and plasma from acute mercuric chloride intoxicated rats as renin substrate material. When the reaction velocity at the constant renin concentration is plotted for various concentrations of angiontensinogen, both substrate materials yielded identical velocities. Influence of plasma from mercuric chloride intoxicated rats upon the velocity of angiotensin formation from normal rat plasma was also examined. Plasma from acute mercuric chloride intoxicated rats did not affect the velocity of angiotensin formation from normal rat plasma and vice versa. These results suggest that acute mercuric chloride intoxication may neither reduce inhibitor(s) nor release activator(s) in plasma which influence the renin-angiotensinogen reaction. The mechanism responsible for augmented pressor response to the exogenous renin in acute mercuric chloride intoxicated rats was discussed.

• 社団法人日本循環器学会の論文
• 1973-11-30

著者

• Takeda Ryoyu

  2nd Department of Internal Medicine,Kanazawa University,School of Medicine

• Takeda Ryoyu

  2nd Department Of Internal Medicine School Of Medicine University Of Kanazawa

• Murakami Mototaka

  2nd Dept. of Intern. Med., Kanazawa Univ., School of Med.

• MORIMOTO SHINPEI

  2nd Department of Internal Medicine, School of Medicine, University of Kanazawa

• Yamamoto Hideki

  2nd Department Of Internal Medicine School Of Medicine University Of Kanazawa

• HIRASAWA KENTARO

  2nd Department of Internal Medicine, School of Medicine, University of Kanazawa

• Murakami Mototaka

  2nd Department Of Internal Medicine School Of Medicine University Of Kanazawa

• Morimoto Shinpei

  2nd Department Of Internal Medicine School Of Medicine University Of Kanazawa

• Hirasawa Kentaro

  2nd Department Of Internal Medicine School Of Medicine University Of Kanazawa

• TAKEDA RYOYU

  2nd Department of Internal Medicine, School of Medicine, University of Kanazawa

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