Hypertension in Chronic Glomerulonephritis and Its Therapy : PANEL DISCUSSION ON DIAGNOSIS AND TREATMENT OF SECONDARY HYPERTENSION
スポンサーリンク
概要
- 論文の詳細を見る
1) In most cases of chronic glomerulonephritis hypertension is usually mild or moderate until the severe renal function disturbance appears. 2) In hypertensive type of chronic glomerulonephritis, renal histological findings, particularly vascular changes, are more progressive than normotensive cases. Thickening or stenosis of renal arteriolar walls in biopsy specimens are correlated with the elevation of the blood pressure, suggesting the usefulness of antihypertensive treatment for hypertension in chronic glomerulonephritis. 3) From the results investigated in 157 dialysis units in Japan, hypertension was controlled by regular hemodialysis with or without antihypertensive treatment in about 3/4 cases of hypertensive patients with chronic renal failure, and in 1 /4 of the cases hypertension was uncontrollable. Hypertension was controlled by bilateral nephrectomy and dialysis in about 3/4 of these uncontrollable hypertensive cases. For the control of hypertension by reqular dialysis, it is important to restrict sodium and water intake severely in the intervals between dialyses. 4) Plasma renin activity was significantly higher in uncontrollable hypertensive patients with chronic renal failure by regular dialysis than in controllable hypertensive cases after hemodialysis. Total peripheral resistance was also higher in uncontrollable hypertensive cases though not statistically significant. Therefore, it is suggested that renin-angiotensin system might play a role in the pathogenesis of hypertension in uncontrollable hypertensive cases by regular dialysis treatment.
- 社団法人日本循環器学会の論文
- 1973-11-30
著者
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Tanaka Sho
Dept. Of Intern. Med.i. Tokyo Univ. School Of Med.
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Nishio Ichiro
Dept. Of Intern. Med.i. Tokyo Univ. School Of Med.
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Sato Rihei
First Department of Internal Medicine, Tokyo Teishin Hospital
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Sato Rihei
First Department Of Internal Medicine Faculty Of Medicine University Of Tokyo
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MASUYAMA YOSHIAKI
First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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TANAKA SHO
First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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NISHIO ICHIRO
First Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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Masuyama Yoshiaki
First Department Of Internal Medicine Faculty Of Medicine University Of Tokyo
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TANAKA Sho
First Department of Internal Medicine, Faculty of Medicine University of Tokyo
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