肺性心の成因に関する実験的研究

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概要

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• It is considered that cor pulmonale necessarily accompanies pulmonary hypertension, which is caused by the increase of pulmonary vascular resistance, as its occassion, and, as the factors of increasing pulmonary vascular resistance, the existence of some functional factors as well as some organic change in pulmonary blood vessel itself should be taken into consideration. Considerable numbers of experimental studies of acute cor pulmonale caused by disturbance of pulmonary blood vessel have been done, while chronic cor pulmonale caused by disturbance of the lungs coming from airway, which is most frequently seen in clinic, has not been studied very much. In order to find the occasion of cor pulmonale, caused by disturbance of the lungs coming from airway, the present writer produced in adult dogs the experimental pulmonary disturbances by infusing resin into their bronchi, and followed up the changes of circulatory dynamics, ventilatory function and others, in terms of the disturbance part and area as well as of time. And then, comparing these findings with pathological ones, he discusses about them here. Materials and Methods Applying the right cardiac catheterization by a modified Bing-Holt's method to this experiment on twenty-four adult dogs, circulatory dynamics, chiefly residual blood volume and, at the same time, ventilatory dynamics were measured and electrocardiogram was recorded as the pre-experimental values. Then, the dogs were divided into the following four experimental groups after infusing resin in the several areas of their bronchi. Group I : Those dogs, into whose bronchi controlling respectively the right second lobeareas of their lungs and the lowerparts of the left first lobes of their lungs the resin was infused. (the dogs infused in the bronchi controlling the 16% pulmonary area)

• 社団法人日本循環器学会の論文
• 1965-09-20

著者

• 安藤 昭寛

  名古屋大学医学部内科第二講座

関連論文

• 実験的肺性心に関する研究(第14報) : 合成樹脂注入犬における急性低酸素血症の肺循環に及ぼす影響について : 日本循環器学会第17回東海地方会総会
• 1)実験的肺性心に関する研究(第15報)(第16回日本循環器学会東海地方会総会) : 肺循環に及ぼす換気変動の影響
• 陽圧呼吸(強制呼吸)による気道・胸腔内圧上昇時の肺循環 : 第15回日本循環器学会東海地方学会総会
• 実験的肺性心に関する研究(第11報) : 低酸素および高炭酸ガス吸息時の肺循環に及ぼす換気変動の影響について : 第26回日本循環器学会総会
• 実験的肺性心の研究 (第9報) : 迷走神経切断実験 : 第11回日本循環器学会東海地方学会総会
• 二, 三降圧剤の臨床的観察 : 第10回日本循環器学会東海地方学会総会
• 実験的肺性心の研究 (第10報) : 合成樹脂注入犬の昇圧機序について : 第25回日本循環器学会総会
• 肺性心の成因に関する実験的研究
• 96) 実験的肺性心に関する研究(第8報) : 気管支閉塞による影響について(第24回 日本循環器学会総会)

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