呼吸変動の肺循環及び肺循環調節に及ぼす影響に関する実験的研究

スポンサーリンク

概要

• 論文の詳細を見る

• The magnitude of pulmonary vascular resistance will be one of the important criteria for pulmonary circulatory function, because it elevates pulmonary arterial pressure to bring about pressure load in the right ventricle of the heart. It being, however, known that, at the pulmonary circulatory system, its anatomical features give some limitation to the application of POISEUILLE-HAGEN Law, the change of pulmonary vascular resistance cannot necessarily result in the active constriction or the dilatation of pulmonary vessels. Meanwhile, since lungs are always influenced with the change of intrapleural pressure, the influence by the change of respiration in terms of its depth or its pattern, should always be taken in consideration. In light of this, the author had the following experiments using normal dogs and experimental pulmonary-hypertension dogs as the subjects : (1) the inflation of intratracheal pressure under the intermittent positive pressure breathing. (2) hyperventilation (by using a body respirator) (3) hypoventilation-lowtidal ventilation-(by using a body respirator) (4) stellectomie (5) intervenous infusion of C_6 (6) vagotomy Through this experimentation, he observed the right ventricular function as well as how the change of each respiratory pattern mentioned in the above experiments affected pulmonary arterial pressure and pulmonary vascular resistance, and affected their regulatory mechanism. Materials and Mehtod As to both the normal dogs and the pulmonary-hypertension dogs (into the bronchi of which resin was infused), the circulatory dynamics, before and during the controlled respiration, and, before and during the blocking of the auto-nomic nervous system, were observed. In other words, the right ventricular function and the pressure-flow relationship in the pulmonary circulatory system were investigated using the cardiac catheterization method and the dye dilution method based on the modified BING-HOLZ method.

• 社団法人日本循環器学会の論文
• 1965-08-20

著者

• 片岡 勝

  名古屋大学医学部第二内科教室

関連論文

• 12)A-a Dの意義と,a-A D_について : 第18回日本循環器学会東海地方学会
• 実験的肺性心に関する研究(第14報) : 合成樹脂注入犬における急性低酸素血症の肺循環に及ぼす影響について : 日本循環器学会第17回東海地方会総会
• 1)実験的肺性心に関する研究(第15報)(第16回日本循環器学会東海地方会総会) : 肺循環に及ぼす換気変動の影響
• 陽圧呼吸(強制呼吸)による気道・胸腔内圧上昇時の肺循環 : 第15回日本循環器学会東海地方学会総会
• 実験的肺性心に関する研究(第11報) : 低酸素および高炭酸ガス吸息時の肺循環に及ぼす換気変動の影響について : 第26回日本循環器学会総会
• 実験的肺性心の研究 (第9報) : 迷走神経切断実験 : 第11回日本循環器学会東海地方学会総会
• 呼吸変動の肺循環及び肺循環調節に及ぼす影響に関する実験的研究
• 実験的肺性心の研究 (第10報) : 合成樹脂注入犬の昇圧機序について : 第25回日本循環器学会総会

スポンサーリンク