Significance of Exercise QT Dispersion in Parients With Coronary Artery Disease Who do not Have Exercise-Induced Ischemic ST-Segment Changes
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概要
- 論文の詳細を見る
The poor sensitivity and the poor predictive value of ST-segment depression have limited the usefulness of the exercise electrocardiogram(ECG)in the diagnosis and evaluation of coronary artery disease(CAD). The QT dispersion(QTD), recorded as the difference between maximal and minimal QT intervals on a 12-lead exercise ECG, is sensitive to myocardial ischemia and may improve the accuracy of exercise testing in patients with CAD who do not show an ST-segment depression. Exercise ECGs were analyzed in 50 subjects who had undergone coronary angiography for clinical indications. None of them showed an ST-segment depression during or after exercise: There were 25 patients with significant coronary artery stenosis and 25 without significant stenosis. The QTD measured before, immediately after, and 1 min after exercise was similar in the 2 groups. The QTD at 3 and 5 min after exercese was significantly greater in patients with CAD than in the controls, and the most marked difference in QTD was observed at 3 min after exercise. A QTD at 3 min after exercise of >60ms had a sensitivity of 80% and specificity of 88% regarding the diagnosis of CAD. When a ΔQTD(post-exercise QTD minus QTD at rest)at 3 min after exercise of >0ms was added to a QTD of >60ms as a condition for positivity, the specificity increased to 96%. QTD measured at 3 min after exercise increases the accuracy of exercise testing in patients with CAD who do not show an ST-segment depression.
- 社団法人日本循環器学会の論文
- 1999-06-20
著者
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Yoshimura Mitsuisa
Department Of Cardiovascular Physiology And Medicine Hiroshima University Graduate School Of Biomedi
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MATSUMOTO Koji
Department of Obstetrics and Gynecology, Institute of Clinical Medicine, University of Tsukuba
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Yoshimura Mitsuisa
Department Of Cardiovascular Physiology And Medicine Graduate School Of Biomedical Sciences Hiroshim
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Yamashita Naoko
Department of Agricultural Chemistry, Faculty of Horticulture, Chiba University
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Watanabe Mitsuaki
Departments Of Cardiology And Internal Medicine Saiseikai Hiroshima Hospital
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Yoshimura Mitsuisa
Departments Of Cardiology And Internal Medicine Saiseikai Hiroshima Hospital
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Yamashita Naoko
Departments Of Cardiology And Internal Medicine Saiseikai Hiroshima Hospital
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Yamashita Naoko
Department Of Agricultural Chemistry Faculty Of Horticulture Chiba University
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Sanuki Eiko
Departments of Cardiology and Internal Medicine, Saiseikai Hiroshima Hospital
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Sumida Yukinobu
Departments of Cardiology and Internal Medicine, Saiseikai Hiroshima Hospital
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Sanuki Eiko
Departments Of Cardiology And Internal Medicine Saiseikai Hiroshima Hospital
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Sumida Yukinobu
Departments Of Cardiology And Internal Medicine Saiseikai Hiroshima Hospital
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Matsumoto Koji
Department Of Obstetrics And Gynecology Graduate School Of Comprehensive Human Science University Of
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Matsumoto Koji
Departments Of Cardiology And Internal Medicine Saiseikai Hiroshima Hospital
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Matsumoto Koji
Department Of Electrical And Electronic Engineering Toyohashi University Of Technology:(present Addr
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