Gender Differences in the Presentation of Adult Obstructive Hypertrophic Cardiomyopathy With Resting Gradient : A Study of 122 Patients
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概要
- 論文の詳細を見る
The present study investigated gender differences among adult patients with obstructive hypertrophic cardiomyopathy (OHCM) and resting gradient. Using outflow gradients >10 mmHg and the presence of asymmetrical septal hypertrophy of the left ventricle as inclusion criteria, 122 patients were identified among patients referred for echocardiographic examinations between May 1990 and October 1996. Clinical, echocardiographical and follow-up data were compared between male and female patients. The female patients were significantly older than male patients (mean age ±SD 66.7±10.5 vs 54.8±12.5 years). The female patients had a smaller interventricular septal wall thickness, less frequent systolic anterior movement of the mitral valve, more frequent association with hypertension, and less frequent association with ischemic heart disease (IHD) and giant T wave inversion. In this study population, adult female patients presented with OHCM 12 years later than males. Whether this represents female patients' reluctance to seek medical attension early, a different disease process that affects predominantly elderly females, or a gender-specific end organ response to aging, hypertention, IHD and other processes, or the protective effects of estrogen remains to be determined.
- 社団法人日本循環器学会の論文
- 1999-10-20
著者
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Ko Yu-lin
First Cardiovascular Division Department Of Internal Medicine Chang Gung Memorial Hospital Chang Gun
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Chu Po-hsien
First Cardiovascular Division Department Of Internal Medicine Chang Gung Memorial Hospital Chang Gun
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Chiang Cheng-wen
First Cardiovascular Division Department Of Internal Medicine Chang Gung Memorial Hospital Chang Gun
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Lin Chin-Lon
Cardiology Division, Department of Internal Medicine, The Buddhist Tzu-Chi General Hospital
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Shaw Cheng-Kuang
First Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang
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Chang Chi-Jen
First Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang
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Lin Chin-lon
Cardiology Division Department Of Internal Medicine The Buddhist Tzu-chi General Hospital
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Chang Chi-jen
First Cardiovascular Division Department Of Internal Medicine Chang Gung Memorial Hospital Chang Gun
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Shaw Cheng-kuang
First Cardiovascular Division Department Of Internal Medicine Chang Gung Memorial Hospital Chang Gun
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