T Wave Alternans for Predicting Adverse Effects of Amiodarone in a Patient With Dilated Cardiomyopathy

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概要

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• An implantable cardioverter defibrillator (ICD) was used in a 62-year-old man with dilated cardiomyopathy (DCM) because of hemodynamically intolerable ventricular tachycardia (VT). Amiodarone was administered after a second episode of ICD discharge. Three weeks later, incessant VT appeared, and DC discharge failed to terminate it. Microvolt T wave alternans (TWA), measured by a spectral method, was observed in this patient with and without amiodarone administration. The onset heart rate with TWA was lower and the alternans voltage was higher with amiodarone than without it. The effects of amiodarone appeared to be related to the exacerbation of VT and an increased defibrillation threshold. TWA might be useful in predicting the proarrhythmic effects of amiodarone in similar cases.

• 社団法人日本循環器学会の論文
• 2001-04-20

著者

• Katagiri Takashi

  Third Dept. of Internal Medicine, Showa University

• Koba Shinji

  Third Department of Internal Medicine, Showa University School of Medicine

• Kobayashi Youichi

  Third Department of Internal Medicine, Showa University School of Medicine

• Ezumi Hitoshi

  Third department of Internal Medicine, Showa University

• Asano Taku

  Third Department of Internal Medicine, Showa University School of Medicine

• Matsuyama Taka-aki

  Department Of Pathology Showa University School Of Medicine

• Tanno Kaoru

  Third Department Of Internal Medicine Showa University

• MATSUYAMA Taka-aki

  Third Department of Internal Medicine, Showa University

• Miyata Akira

  Third Department of Internal Medicine, Showa University School of Medicine

• Miyata Akira

  Third Department Of Internal Medicine Showa University School Of Medicine

• Adachi Taro

  Third Department Of Internal Medicine Showa University School Of Medicine

• Kobayashi Youichi

  The Third Department Of Internal Medicine School Of Medicine Showa University

• Kobayashi Youichi

  Third Department Of Internal Medicine Showa University School Of Medicine

• Baba Takao

  Third Department of Internal Medicine, Showa University, School of Medicine

• Obara Chiaki

  Third Dept.of Internal Med., Showa Univ.School of Med.

• Katagiri Takashi

  Third Department Of Internal Medicine Showa University School Of Medicine

• Baba Takao

  Third Department Of Internal Medicine Showa University School Of Medicine

• Ryu Shunsho

  Third Department Of Internal Medicine Showa University School Of Medicine

• Obara Chiaki

  Third Department Of Internal Medicine Showa University Of Medicine

• Matsuzaki Akihiro

  The Third Department Of Intemal Medicine Showa University School Of Medicine

• Matsuyama Takaaki

  Third Department Of Internal Medicine Showa University School Of Medicine

• Ezumi Hitoshi

  Third Department Of Internal Medicine Showa University

• Katagiri Takashi

  Third Department Inter Nat Medicine Showa University

• Koba Shinji

  Third Department Of Internal Medicine Showa University School Of Medicine

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