Torsade de Pointes Induced by Intravenous and Long-Term Oral Amiodarone Therapy in a Patient With Dilated Cardiomyopathy
スポンサーリンク
概要
- 論文の詳細を見る
A 70-year-old woman with dilated cardiomyopathy and ventricular tachyarrhythmia was initially treated in 1990 with intravenous amiodarone (240mg). She developed a junctional escape rhythm (48 beats/min) with QT prolongation (QT:0.68s) and 8h later developed torsade de pointes (TdP). Because other antiarrhythmic drugs did not suppress the arrhythmia, oral amiodarone (100mg/day) was started in 1995, 7 weeks before she presented with congestive heart failure. The QT prolongation (QTc:0.64) increased after administration of dopamine, and TdP again developed. This case suggests that amiodarone induces proarrhythmias by different mechanisms when administered intravenously or orally.(Jpn Cire J 2001;65:188-192)
- 社団法人日本循環器学会の論文
- 2001-02-20
著者
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Kuga Keisuke
Cardiology Department of Internal Medicine, University of Tsukuba Graduate School of Comprehensive H
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Yamaguchi Iwao
Cardiology Department of Internal Medicine, University of Tsukuba Graduate School of Comprehensive H
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Kuga Keisuke
Health Administration Center Institute Of Clinical Medicine University Of Tsukuba:japanese Associati
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Yamada Satsuki
Cardiovascular Division Department Of Internal Medicine University Of Tsukuba
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Yamaguchi Iwao
Cardiology Department Of Internal Medicine University Of Tsukuba Graduate School Of Comprehensive Hu
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Kuga Keisuke
Cardiology Department Of Internal Medicine University Of Tsukuba Graduate School Of Comprehensive Hu
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Kuga Keisuke
Department Of Internal Medicine Institute Of Clinical Medicine Graduate School Of Comprehensive Huma
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