Selenium Status in an Iodine Deficient Population of the West Ivory Coast (<SPECIAL ISSUE>INTRIGUING TOPICS IN PHYSIOLOGICAL ANTHROPOLOGY)
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概要
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Selenium is an essential trace element which is part of the active site of seleno-dependent glutathione peroxidase and type 1 deiodinase. Therefore, it plays a key role in thyroid hormone metabolism. The present work was undertaken in order to evaluate selenium status in two Ivory Coast populations: the first with high (Glanle) and the second with low (Abidjan) prevalence of iodine deficiency. Selenium, glutathione peroxidase, glutathione reductase, glutathione and diglutathione were determined in blood and/or urine. In plasma and erythrocytes, selenium and glutathione peroxidase were dramatically low in Glanle. Compared to Abidjan, selenium, glutathione peroxidase, vitamin E and riboflavin status were decreased whereas diglutathione was increased in Glanle. The results clearly demonstrate a selenium deficiency and suggest an oxidant stress in Glanle. Causes and consequences of this selenium deficiency and oxidant stress remain to be determined.
- 日本生理人類学会の論文
著者
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Faure Henri
Department Of Integral Biology Chug
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Arnaud Josiane
Department Of Integral Biology Chug
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Malvy Denis
Centre Rena Labusquiere and INSERM U 230, University Victor Segalen
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Richard Marie-Jeanne
Department of Integral Biology, CHUG
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Chaventre Andre
Laboratory for Anthropology and Genetic Demography, University Victor Segalen
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Malvy Denis
Centre Rena Labusquiere And Inserm U 230 University Victor Segalen
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Chaventre Andre
Laboratory For Anthropology And Genetic Demography University Victor Segalen
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Richard Marie-jeanne
Department Of Integral Biology Chug