F-0918 表面修飾したチタン粉末焼結体 : 強度と生体融和機能の協調設計(S44-2 生体材料研究の新展開(2))(S44 生体材料研究の新展開)

概要

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It is intended that proteins immobilize on the surface of titanium implants. This is accomplished by the porous titanium compacts and the precipitation of calcium phosphate on the surface of titanium because proteins can easily immobilize on the calcium phosphate crystals. Sintered compact both with biological functions of proteins and high strength as metals was developed. Three methods were applied to arrange the specimens. 1) The powders were sintered in the carbon dies to the shape by spark plasma sintering (SPS). After that, the compact was immersed in aqueous solution of CaO. 2) The powders were mixed with CaO particles, and sintered by SPS. 3) The powders were immersed in aqueous solution of CaO. The powders with surface modification were sintered by SPS. The compacts were then immersed in Hanks' solution. The amount of precipitation of the calcium phosphate in the compacts was measured and compared between the sintering methods. The sintered compact, which was titanium powder particles covered with calcium phosphate, could absorb large amount of proteins.
一般社団法人日本機械学会の論文
2001-08-22