非接触レーザー組織血流測定法

概要

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A non-contact laser (tissue) blood flowmeter (LBF) which allows us to measure "tissue blood flow" (local blood flow in unit tissue volume) without contacting a probe with tissue was designed. The reflection from tissue surface deeply influences the measurement value obtained from an ordinary LBF when a probe is separated from the tissue becaus of its algorithm. The non-contact LBF utilizes the polarization of laser light to eliminate the reflection, and an electronic circuit to reduce artifacts caused by the change of the distance between the probe and the tissue sample being studied. The probe of the non-contact LBF consists of optical fibers and a special polarizer. The tissue being studied is illuminated by a linearly polarized light and the perpendicularly polarized light is detected. The non-contact LBF was compared with an ordinary LBF using a tissue blood flow model and human fingers. The results showed that the measurement value obtained by the non-contact LBF was not influenced by the reflecdtion from the surface of the model and was not much affected by the change of the distance between the probe and the model. The recordings of digital blood flow changes obtained by the non-contact LBF agreed very well with those of the ordinary LBF.
日本医療機器学会の論文
1993-07-01