ホルマリンガス滅菌消毒用の化学的インジケータの検討

概要

論文の詳細を見る
The authors developed a chemical indicator for formaldehyde gas sterilization. An exposure to 3,500-5,000 ppm formaldehyde vapor for three hours at 40 degrees centigrade was chosen as an optimal sterilizing condition. Bacteriological tests using Bacillus subtilis golbigii and Bacillus stearothermophilus confirmed its appropriateness. Among four kinds of dye-mixture with various speeds of reaction to formaldehyde, one which changes its light reflectance at 530 nm from 5% to more than 35% only after achieving the above condition was selected for the indicating dye. As post-sterilization retention of formaldehyde on the indicator strip might induce delayed change in its color to give a false-positive result, it must be made as small as possible. Synthetic paper made of 100% polypropylene retained for less form aldehyde than ordinary papers (20 ppm vs. 20,000 ppm at 24 hours post-sterilization). Therefore, the indicating dye was applied on a piece of the synthetic paper. The authours believe that the use of this indicator serves as practical method for the confirmation of the adequate formaldehyde sterilization.
日本医療機器学会の論文
1990-03-01