ディスポーザブル医材の放射線滅菌線量の検討(III) : 月経処理用タンポンのMicrobial Burdenの調査および滅菌線量の算出

概要

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The microbial burden and dose setting for radiation sterilization of tampon for menstrual hygiene were examined, and the following results were obtained.1. The maximum and minimum contaminants per a tampon were 100 and 0,and the average was 46.1.2. The 91.2% of the 125 strains isolated from the tampon was identified as bacilli by the microbiological and biochemical activites, and Bacillus pumilus compried 35.2% of the srains. B. pumilus and B. megaterium spores indicated the highest radioresistance among those contaminants and both D- values were 0.22 Mrad.3. The difference in the D-value was not found for the radioresistance of standard strain carried on a tampon and a glass fiber filter.4. The sterilization dose (SD) was calculated to be 1.10 Mrad by the formula SD=D x log (No/N), while the SD was 0.90 and 0.76 Mrad, respectively, for the microbial burden in formations and steility tests.From above ressults, it is supposed that the sterility assurance level in 10^<-3> can be achieved by irradiating the dose less than 1 Mrad.
日本医療機器学会の論文
1985-05-01