3.腹水肝癌の腹水誘因物質.第1報(第2回プラズマキニン研究会)

概要

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When ascites hepatoma 130 was transplanted in peritoneal cavity of rat, the ascites volume was rapidly increased after one weak and the number of the cancer cells decreased at the same time. Though the cancer cells contained no accelerating of the blood vessels. It was comfirmed that the composed showing the activity in question was formed in supernatant fluid of the ascties. This substance is supposed to be a low moleculer weight protein or peptid, because the fraction passed most slowly through sephadex G25 column. On the other hand, homochlorocyclizine which is the antagonist of kinin and serotonin was injected in rats 2.5 mg every day after the transplantation of cancer cell. The results showed that the permeability was inhibited and the survival was postponed few days.
一般社団法人日本アレルギー学会の論文
1968-04-30