家屋塵性気管支喘息患児に対するScratch法による減感作療法の試み

スポンサーリンク

概要

• 論文の詳細を見る

• The hyposensitization treatment with house dust allergen followed "the Scratch-Method" were carried out to 131 cases of asthmatic children. The technique which was nominated here as "the Scratch-Method" had been devised in our clinic at first time, was executed as followed; the several scratchings in the length of a certain mm in I square centimeter, made mildly be bleeding enough, were performed on the extensor site of arm and there dropped and smeared the allergen extracts. And then gradually made prolong the dropping and smearing duration in schedule through which made attempt to increase of the dosis of allergen and at the same time made also prolong the interval of treatment with the tide of therapeutic process. The allergen extracts, used in this study, were consisted with that of the mixture in which mixed equally in volume of 10 sorts of house dust allergen extracts which were extracted with the CoCa solution and which had been usually utilized to the scratch test in our clinic. The subjects were observed the process for from 15 months to 32 months and the author have attempted to estimate to the effects of this therapeutic trial. The effects was found out in 80.9% followed the criteria which had been established by the meeting society of pediatric allergy, and in 85.0% were improved from the view of point tht of the Savidge, therefore, it is able to be admitted that the effects of this trial therapy had not significantly differed from that of the usual technique as the intradermal injection. Some observation made in this study about relationship of the effects to the term of treatment, sex, and appearance of the side effect was also noted. 1) The more improved, the longer treated in its term and the more frequent treated. 2)There was no significant difference of the effect in sex. 3) The side effects were noted as the occurrence of urticaria, turned severe eczema, and immediated or delayed reaction etc. And provocated mild asthmatic attacks were checked 45.8% in its occurrence. This study is at all the first trial one which little work has been done in any literatures, so that the author methinks about some merits and faults in this treatment and then from these results, emphasize that this attempt is one of the reliable and useful therapeutic method of hyposensitization.

• 日本アレルギー学会の論文
• 1965-07-30

著者

• 林 英之

  名大小児科

• 林 英之

  名古屋大学小児科

関連論文

• 113. 慢性ジンマシンの心身医学的研究(第14回日本アレルギー学会総会)
• 4)小児気管支喘息の病態生理学的研究 第2報 : 誘発発作前後における抗体価並びに皮膚感作抗体価の変動とそのポリグラフについて(I-4 小児喘息)
• 家屋塵性気管支喘息患児に対するScratch法による減感作療法の試み
• 8. 小児科気管支喘息の病態生理学的研究 : 第1報 ポリグラフにみられた誘発試験発作像について(第14回日本アレルギー学会総会)
• 2. 血小板及び白血球減少指数よりみた皮内反応の検討 : 特に家塵抗原性気管支喘息を中心にした(第14回日本アレルギー学会総会)
• 1. 花ガツオおよび家屋塵抗原性についての比較検討(予報)(第14回日本アレルギー学会総会)
• 17.気管支喘息における家塵抗原によるスクラツチ法脱感作療法の効果(第13回日本アレルギー学会総会)
• 4. 気管支喘息の発作誘発試験(第12回日本アレルギー学会総会)

スポンサーリンク