小児気管支喘息と空中真菌類との関係に関する研究 : 第I篇小児気管支喘息に対する各種真菌抗原による皮膚反応成績, ならびに2, 3の血清学的検索成績について

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Studies on skin tests with mold allergens, some serological studies and hyposensitization thrapy with mixed mold extracts were as follows; 1) Five mold extracts were used for skin tests. They were scratch type of powdered allegens made by Hollister-Stier laboratories (Aspergillus, Penicillium, Hormodendrum, Rhizopus and Alternaria). One hundred twelve asthmatic children were tested with the mold extracts, fifty six cases (50%) were positive. Control group of nonasthmatic children were only 10 per cent positive. 2) Mixed mold allergens mde by Kudansake hospital were used for intradermal tests. One hundred eight-three asthmatic children were tested with our mixed mold allergens. Fifty one cases (27.3%) were positive. Control group of nonasthmatic children (20 cases) were negative. 3) PTT with mold extracts made by Hollister-Stier laboratories have been done in 13 cases. Five of them (38.4%) was positive and mixed mold made by Kudansaka hospital have been done in 15 cases, 14 of them (93.3%) was positive. 4) BDB were all positive in 11 cases. 5) Two years follow up studies of hyposensitization thrapy with mixed mold extracts showed no asthmatic attacks in 10 cases (58.9%) in 17 cases, but symptomatic therapy showed in only 6 cases (15.0%) in 40 cases. The result of hyposesitization therapy group were excellent compared with symptomatic therapy group.
1965-03-30