CHIRONOMID MIDGE ALLERGY

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概要

• 論文の詳細を見る

• Chironomidae larvae and midges cause allergic reactions in approximately 20 percent of exposed people; predominantly aquarists using insect larvae as fish food and environmentally exposed subjects living in areas abounding in water are affected. Our studies include 642 subjects of whom 205 are aquarists; 85 are occupationally and 352 environmentally exposed people. 123 of them were shown to be sensitized to these insects. Using highly purified allergens, we could demonstrate that Chironomidae hemoglobins (Chi t I) represent the major allergenic components causing rhinitis, conjunctivitis and bronchial asthma. Considerable immunological cross-reactivity exists between hemoglobins of the same and closely related Chironomidae species. Genetic factors seem to be important for the susceptibility of this type of allergy. In studies with peptides of Chi t I component III, we identified several epitopes recognized by human IgE antibodies and/or T-cells.

• 日本アレルギー学会の論文
• 1992-02-28

著者

• Baur X

  Ruhr‐univ. Bochum Bochum Deu

• Baur Xaver

  Professional Associations' Research Institute for Occupational Medicine the Ruhr University of Bochu

• Baur Xaver

  Professional Associations' Research Institute for Occupational Medicine the Ruhr University of Bochum

関連論文

• CHIRONOMID MIDGE ALLERGY

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