腸内細菌とくに大腸菌属による生態の感作とその意義に関する研究 : 第8報培養白血球反応を指標としての大腸菌及び赤痢菌菌体物質による遅延型アレルギー反応の証明

概要

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Two groups of guinea pigs were sensitized with E. coli 0-13 or Sh. flexneri 2b with adjuvant or not respectively. Leucocytes were isolated and pooled from the blood of the sensitized guinea pigs and the tissue culture type test of leucocytes were performed by applying the respective antigens. The tissue culture type test of leucocytes were negative, when the leucocytes obtained from the group of the guinea pigs sensitized by the use of adjuvant were used, though Schultz-Dale reaction of the isolated guinea pig intestine of the group were positive. However, the test was positive, when the leucocytes isolated from the group sensitized without adjuvant were used and Schultz-Dale reaction of the isolated guinea pig intestine of this group were almost positive.
1961-02-28