花粉喘息に関する研究 特にRagweed花粉の臨床的並びに血清学的研究
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概要
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The antigenicity of the pollens of American giant and common ragweed which are regarded as the most important factor in asthma and hey feber and butakusa which grows in Japan, originating for the American ragweed botanically are compared, of 120 asthma patients who were intradermally tested with butakusa pollen extract, 15 showed a positive reaction (2: 3 plus positive, 3: 2 plus positive, 10: 1 plus positive). 10 of these positive patients were intradermally tested with a further 2 pollen extracts-American giant and common ragweed, and also were exposed to the above mentioned 3 pollen. Three cases showed wheezing after nasal inhalation of butakusa pollen, 1 case after nasal inhalation of giant ragweed, 1 case after common ragweed pollen. 8 patients were tested by the passive transfer method of Prausnitz Kuestner and 3 showed a positive result. But there was no definite correlation between the positive result and clinical symptom. Sera of intradermal test positive and negative patients were tested for hemagglutinability of tannic acid and protein treated red blood cells, but hemagglutination did not develop. The author performed antigen-antibody studies with the precipitation ring test, Ouchterlony test and hemagglutination test, using tannic acid and protein treated red blood cells, and found that giant, common and butakusa pollen are serologically different and butakusa pollen is far different form giant ragweed pollen and even different from common ragweed pollen, too.
- 一般社団法人日本アレルギー学会の論文
- 1960-12-01