モルモットに於ける種々なショック時の酸素系変動に関する組織化学的研究

概要

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The change of the enzymatic system of the guinea pig by anaphylaxis, Forssman shock, histamine or acetylcholine shock and the injection of the bacterial exotoxin (diphtheria, tetanus) were investigated histochemically. As the enzyme in the tissues alkali and acid phosphatase (Kolle method), succinate dehydrogenase (Wechstein et Meisel method) and amine oxydase (reduction method with kallium tellurite acid by Takamatsu) were studied. By these histochemical methods the activities and localizations of the enzymes in the normal and shocked guinea pigs were clarified. From the results of the experiments the change of the enzyme by various shocks depend upon the kinds of the enzyme, the tissue and the localization of the cells. Comparing to the control group, the enzymatic activity after the shocks was observed to be increased in some cases, but in other cases it was observed to be decreased. The most remarkable change of alkali and acid phosphatase, lipase, cholinesterase, succinate dehydrogenase and amine oxydase were observed in anaphylaxis, next in Forssman shock and then in the case of the guinea pig injected the bacterial toxin. Not a remarkable change was observed in cholinesterase in histamine and acetylcholine shocks.
日本アレルギー学会の論文
1960-01-01