ウサギの耳における遷延アルツス現象と副腎皮質ホルモン剤によるその像の歪み

概要

論文の詳細を見る
In 1951 Okabayashi demonstrated in the sensitized rabbit a characteristic focal lesion induced by the repeated subcutaneous injections of antigen at the same site of the back. It was later designated as "prolonged Arthus phenomenon" by him. The author studied on the prolonged Arthus phenomenon which had been brought our in the sensitized rabbit following the repeated subcutaneous injections of egg whit at the same site of the auricule. In twenty-fifth day of the experiment there occurred so-called allergic demarcating inflammation; that is a prolonged granulating inflammation characterized by formation of a layer of the fibrinoid necrosis. More-over, it was histologically shown that the allergic demarcating inflammation was subject to an antiphlogistic or prophlogistic influence following the administration of cortisone or DOCA respectively. The administration of cortisone resulted the development of a markedly weakened demarcating inflammation, while that of DOCA was followed by a severe demarcation with the deeper demarcating inflammation.
日本アレルギー学会の論文
1960-01-01