Radiation Carcinogenesis in Mouse Skin and Its Threshold-like Response

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概要

• 論文の詳細を見る

• Experiments on the dose-response of tumor development induced by repeated local beta irradiation of the back of mice are summarized. Results indicated a 100% tumor incidence on irradiation at 2. 5-11. 8 Gy per exposure (dose-saturation effect) and the threshold-like dose response at lower doses. The mechanism underlying these phenomena is discussed on the basis of the tissue-misrepair model, that is misrepair caused by repeated stimulation of cell growth after repeated tissue injury.

• 日本放射線影響学会の論文

著者

• TANOOKA Hiroshi

  Radiobiol. Div. Natl. Cancer Res. Inst

• Ootsuyama Akira

  Radiobiology Division National Cancer Center Research Institute

• Tanooka Hiroshi

  Radiobiology Division National Cancer Center Research Institute

関連論文

• Mutations of tunor suppressor gene p53 ila nouse tunors induced by repeated beta radiation
• Mouse Tumors Induced by Repeated Beta Radiation : Homologous Recombination between p53 and Its Pseudogene
• Characteristics of the effect of repeated radiation on cancer induction.
• Radiation Carcinogenesis in Mouse Skin and Its Threshold-like Response

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